PublishYou are here: Home » Products » Chemicals » Machinery & Equipment » Thermal Process Equipment

Hydroxypropyl Gamma Cyclodextrin (HP-γ-CD)
Original
price: Negotiable
minimum:
Total supply:
Delivery term: The date of payment from buyers deliver within days
seat: Shandong
Validity to: Long-term effective
Last update: 2023-10-24 07:54
Browse the number: 120
inquiry
Company Profile
 
 
Product details
Quick Details

 

Name

Hydroxypropyl gamma cyclodextrin (HP-γ-CD)

CAS No.

128446-34-4

Molecular Formula

C48H80-nO40.(C3H7O)n

Molecular Weight

1297.2+n.(58.1)

Appearance

White powder, insipid, innocent

Assay

≥98％

Classification

Pharmaceutical Grade

Quality standard

Enterprise Standard

 

Molecular structuer:

 

Product Introduction

 

Hydroxypropyl gamma cyclodextrin (HP-γ-CD) is a derivative of gamma Cyclodextrin. It can crosslink to form longer polymers. It is a very useful chemical for Supramolecular chemistry. Other application field: solubilizing macromolecules, cultivating cells, etc. It is similar to beta cyclodextrin, but it can interact with larger molecules.

 

Hydroxypropyl gamma cyclodextrin manufacturer-Shandong Binzhou Zhiyuan Biotechnology Co., Ltd which has completed registration with FDA, and the registration information is as follows:

Company name: Shandong Binzhou Zhiyuan Biotechnology Co., Ltd

FDA ESTABLISHMENT IDENTIFIER (FEI No.)：3011680310

ESTABLISHMENT ADDRESS: Boxing Economic Development Zone,, Binzhou, Shandong 256500, China (CHN)

DUNS: 548171477

 

Product Specification

 

Test Standard

Enterprise standard

ITEMS

SPECIFICATION

Appearance

White powder, insipid, innocent

Assay

≥98％

Absorbance

The absorbance at 230~350nm should not exceed 0.50, while at 350~660nm should not exceed 0.5

PH

6.0 ~ 9.0

Loss on Drying

≤10.0％

Gamma cyclodextrin

≤1.5％

Propylene glycol

≤0.5％

Residue on Ignition

≤0.2％

Heavy Metal

≤10ppm

Molar Substitution

0.5-0.7

Microbiology

Aerobic microorganism

≤1000CFU/g

Moulds & yeasts

≤100CFU/g

Escherichia Coli

Absence

 

Features

 

Hydroxypropyl)-γ-cyclodextrin 's water solubility increase to 80g/100ml (25 C) furtherly , and hydroxypropyl gamma cyclodextrin is no longer a single pure product but the coexistence of multiple substituted compounds, with guest molecules when wrapping is not easy to generate inclusion crystallization. Overall, hydroxypropyl- gamma cyclodextrin has a higher solubility in water and stronger anti crystallization ability.

 

Application In the field of Pharmaceutical：

 

1

Hydroxypropyl gamma cyclodextrin (HP-γ-CD) can enhance drug solubility, stability, and bioavailability.

2

It can controlled release of encapsulated substances.

3

It can regulate the release rate and time of the drug to achieve better therapeutic effect In the drug delivery system.

4

Solubilization and solubilization, anti-oxidation, odor, slow release, targeted drug delivery, etc.

 

Packing & Storage

 

● Internal packing: packed PE bag, then put into aluminum foil bag

● Storage: Preserve well-closed containers protect from moisture.

● Label: according to customers' request.

● Outer packing: packed in drum.

● Packing:100g/bag, 1kg/bag, 2kg/bag, 10kg/bag/drum, 20kg/bag/drum

 

Delivery

 

1

Stock:

Goods in stock

2

Delivery:

Delivery goods within 1-3 workdays.

3

Loading location:

factory of Binzhou Zhiyuan(China)

4

Shipping:

FOB, CIF, CFR, DDU.....

 

 

 

Certificate

 

 

 

FAQ

 

Q: Do you accept sample order?

A: We accept sample orders.MOQ: 0.1kg.

Q: How to confirm the product quality before placing orders?

A: It is recommended to test the quality of the samples before placing an order, as we can ensure that the quality of the order is consistent with the quality of the samples.

Q: Do you supply product report?

A: Yes. We'll give you product analysis report before shipping.

Q: Is there a discount?

A: Different quantity has different discount.

 

Application case

 

In olopatadine hydrochloride Ophthalmic Solution, Hydroxypropyl gamma cyclodextrin (HP-γ-CD) is the best forming agent.

 

Olopatadine eye drops are solution agents, which are used to treat signs and symptoms of allergic Conjunctivitis. It can be used for the treatment of bacterial Conjunctivitis, Keratitis, dacryocystitis, postoperative infection and other external eye infections.

 

Hydroxypropyl gamma Cyclodextrin can significantly enhance the solubility of Olopatadine in aqueous solution, reduce the bitterness of Olopatadine, and greatly improve the stability of olotadine. Because of the inclusion effect of hydroxypropyl gamma Cyclodextrin on Olopatadine, Olopatadine can be slowly released, which can increase the administration time in the actual administration process.

http://www.icyclodextrin.com/

Total0bar [View All]  Related Comments
 
more»Other products
Hydroxypropyl Gamma Cyclodextrin (HP-γ-CD) Gamma-Cyclodextrin 2-hydroxypropyl Ethers [128446-34-4] (2-hydroxypropyl)-gamma-cyclodextrin( HPGCD) CAS 128446-34-4 (2-Hydroxypropyl)-γ-Cyclodextrin Hydroxypropyl-γ-Cyclodextrin (HP-gamma-CD)

[ Products search ] [ favorites ] [ Tell friends ] [ Print ] [ Close ]